SJ-01

Sunan Sinadari:

(E) -1- (3- (3,4,5-trimethoxyphenyl)acryloyl) -5,6-dihydropyridin-2 (1H) -daya

Lambar SMILES:

O=C1C=CCCN1C(/C=C/C2=CC(OC)=C(OC)C(OC)=C2)=O

Lambar InChi:

InChi=1S/C17H19NO5/c1-21-13-10-12(11-14(22-2)17(13)23-3)7-8-16(20)18-9-5-4-6- 15(18)19/h4,6-8,10-11H,5,9H2,1-3H3/b8-7+

InChi Key:

VABYUZNAVQNPG-BQYQJAHWSA-N

Mabuɗin kalma:

20069-09-4;CAS:20069-09-4;CAS:20069-09-4;Piperlongumine; Piplatine.

Solubility:Mai narkewa a cikin DMSO

Ajiya:Dry, duhu kuma a 0 - 4 C na gajeren lokaci (kwanaki zuwa makonni) ko -20 C na dogon lokaci (watanni zuwa shekaru).

Bayani:

Piperlongumine, wanda aka fi sani da Piplartine, shine alkaloid / amide mai aiki na ilimin halitta daga barkono, kamar daga barkono mai tsawo (Piper longum L. - Piperaceae). Dogon barkono yana daya daga cikin mafi yawan amfani da maganin Ayurvedic, wanda ake amfani dashi don magance cututtuka da yawa, ciki har da ciwace-ciwace. Ayyukan pharmacological da aka ruwaito na piplartine sun haɗa da cytotoxic, genotoxic, antitumor, antiangiogenic, antimetastatic, antiplatelet aggregation, antinociceptive, anxiolytic, antidepressant, anti-atherosclerotic, antidiabetic, antibacterial, antifungal, leishmanicidal, trypanocidal, da kuma ayyukan s. Daga cikin tasirin magungunan magunguna da yawa na piplartine, kayan anticancer shine mafi alƙawarin.

Manufa: Piperlongumine alkaloid ne wanda ke hana canjin myofibroblasts ta hanyar hana hanyar siginar erk1/2