Ertugliflozin

Sunan Sinadari:

(1S,2S,3S,4R,5S) -5- (4-chloro-3- (4-ethoxybenzyl) phenyl) -1- (hydroxymethyl) -6,8-dioxabicyclo[3.2.1] octane-2,3 ,4-triol

Lambar SMILES:

"CCOC1=CC=C(C=C1)CC2=C(C=CC(=C2)C34C(C(C(C(O3)(CO4)CO)O)O)O)Cl"

Lambar InChi:

"InChi=1S/C22H25ClO7/c1-2-28-16-6-3-13(4-7-16)9-14-10-15(5-8-17(14)23)22-20(27) 18(25)19(2 6)21 (11-24,30-22)12-29-22/h3-8,10,18-20,24-27H,2,9,11-12H2,1H3/t18-,19-,20+ ,21-,22-/m0/s1 "

InChi Key:

"MCIACXAZCBVDEE-CUUWFGFTSA-N"

Mabuɗin kalma:

Ertugliflozin, PF 04971729, MK-8835,1210344-57-2

Solubility:Mai narkewa a cikin DMSO

Ajiya:0 - 4°C na gajeren lokaci (kwanaki zuwa makonni), ko -20°C na dogon lokaci (watanni).

Bayani:

Ertugliflozin, wanda kuma aka sani da PF-04971729, mai ƙarfi ne kuma mai zaɓin mai hanawa na 2 mai dogaro da sodium da kuma ɗan takarar asibiti don kula da nau'in ciwon sukari na 2. Nazarin asibiti ya nuna cewa Ertugliflozin (1-25 MG / rana) yana haɓaka sarrafa glycemic, nauyin jiki da hawan jini a cikin marasa lafiya tare da T2DM da ke ƙarƙashin ikon sarrafa metformin, kuma an jure shi sosai.

Saukewa: SGLT-2