BAY-1895344
Cikakken Bayani
Tags samfurin
| Girman Kunshin | samuwa | Farashin (USD) |
| 10mg | A Stock | 210 |
| 100mg | A Stock | 480 |
| 1g | A Stock | 950 |
Sunan Sinadari:
(R) -3-methyl-4- (4- (1-methyl-1H-pyrazol-5-yl) -8- (1H-pyrazol-5-yl) -1,7-naphthyridin-2-yl) morpholine
Lambar SMILES:
CN1N=CC=C1C2=CC(N3[C@H](C)COCC3=NC4=C(C5=CC=NN5)N=CC=C24.[H]Cl
Lambar InChi:
InChi=1S/C20H21N7O.ClH/c1-13-12-28-10-9-27(13)18-11-15(17-5-8-23-26(17)2)14-3-6- 21-20 (19 (14)24-18)16-4-7-22-25-16;/h3-8,11,13H,9-10,12H2,1-2H3,(H,22,25) ;1H/t13-;/m1./s1
InChi Key:
KWQNBYGUBHMRPY-BTQNPOSSSA-N
Mabuɗin kalma:
1876467-74-1;CAS:1876467-74-1;CAS:1876467-74-1;BAY-1895344,BAY1895344,BAY 1895344
Solubility:Mai narkewa a cikin DMSO
Ajiya:0 - 4°C na gajeren lokaci (kwanaki zuwa makonni), ko -20°C na dogon lokaci (watanni).
Bayani:
BAY-1895344 mai zaɓin ATR (ataxia-telangiectasia da furotin mai alaƙa da Rad3) mai hanawa wanda ke hana yaɗuwar nau'ikan layin ƙwayoyin ƙwayar cuta na ɗan adam (tsakiyar IC50 = 78 nM). BAY-1895344 an ƙera shi don kula da marasa lafiya tare da ci gaba da ciwace-ciwacen ciwace-ciwacen ƙwayar cuta da ƙwayoyin lymphomas, kuma yana fuskantar gwaji na asibiti na lokaci na aminci da haƙuri ga masu cutar kansa.
Saukewa: ATR