ABBV-744

Ngalan sa Kemikal:

N-ethyl-4-(2-(4-fluoro-2,6-dimethylphenoxy)-5-(2-hydroxypropan-2-yl)phenyl)-6-methyl-7-oxo-6,7-dihydro-1H -pyrrolo [2,3-c] pyridine-2-carboxamide

SMILES Code:

O=C(C(N1)=CC(C(C2=CC(C(C)(O)C)=CC=C2OC3=C(C)C=C(F)C=C3C)=CN4C)=C1C4 =O)NCC

InChi Code:

InChI=1S/C28H30FN3O4/c1-7-30-26(33)22-13-20-21(14-32(6)27(34)24(20)31-22)19-12-17(28(28) 4,5)35)8-9-23(19)36-25-15(2)10-18(29)11-16(25)3/h8-14,31,35H,7H2,1-6H3, (H,30,33)

InChi Key:

OEDSFMUSNZDJFD-UHFFFAOYSA-N

Keyword:

ABBV-744, ABBV 744, ABBV744, 2138861-99-9

Solubility:Matunaw sa DMSO

Pagtipig:0 - 4°C alang sa mubo nga termino (mga adlaw ngadto sa mga semana), o -20°C alang sa taas nga termino (mga bulan).

Deskripsyon:

Ang ABBV-744 usa ka BDII-selective BET bromodomain inhibitor nga giimbestigahan aron matambal ang AML ug metastic castration-resistant prostate cancer.

Target: BET bromodomain