Ifebemtinib፣ BI 853520

የኬሚካል ስም

4-[[4-[(2,3-Dihydro-2-methyl-3-oxo-1H-isoindol-4-yl) oxy]-5- (trifluoromethyl)-2-pyrimidinyl] አሚኖ]-2-ፍሎሮ- 5-ሜቶክሲ-ኤን- (1-ሜቲል-4-ፓይፔሪዲኒል) ቤንዛሚድ

የፈገግታ ኮድ፡-

O=C(NC1CCN(C)CC1)C2=CC(OC)=C(NC3=NC=C(C(F)(F)F)C(OC4=CC=CC(CN5C)=C4C5=O)= N3)C=C2F

የኢንቺ ኮድ

InChi=1S/C28H28F4N6O4/c1-37-9-7-16(8-10-37)34-24(39)17-11-22(41-3)20(12-19(17)29)35- 27-33-13-18(28(30፣3) 1)32)25(36-27)42-21-6-4-5-15-14-38(2)26(40)23(15)21/h4-6,11-13,16H,7- 10፣14H2፣1-3H3፣(H፣34፣39)(H፣33፣35፣36)

የኢንቺ ቁልፍ፡

ULMMVBPTWVRPSI-UHFFFAOYSA-N

ቁልፍ ቃል፡

እ.ኤ.አ.

መሟሟት;በዲኤምኤስኦ ውስጥ የሚሟሟ, በውሃ ውስጥ አይደለም

ማከማቻ፡0 - 4 C ለአጭር ጊዜ (ከቀናት እስከ ሳምንታት), ወይም -20 C ለረጅም ጊዜ (ወራት).

መግለጫ፡-

Ifebemtinib (BI 853520) የአፍ እንቅስቃሴ ያለው የትኩረት adhesion kinase (FAK) ኃይለኛ ተከላካይ ነው።

ዒላማ: FAK ጠንካራ አጋቾቹ