AZD0780;EX-A6975;laroprovstatum; laroprovstat

የኬሚካል ስም

6'-(((1S,3S)-3-((5- (difluoromethoxy) pyrimidin-2-yl)amino)cyclopentyl)amino)-2H-[1,3'-bipyridin] -2-አንድ

የፈገግታ ኮድ፡-

O=C1N(C=CC=C1)C2=CN=C(N[C@@H]3C[C@H](CC3)NC4=NC=C(OC(F)F)C=N4)C= C2

የኢንቺ ኮድ

InChi=1S/C20H20F2N6O2/c21-19(22)30-16-11-24-20(25-12-16)27-14-5-4-13(9-14)26-17-7-6- 15 (10 -23-17)28-8-2-1-3-18(28)29/h1-3,6-8,10-14,19H,4-5,9H2,(H,23,26)(H ,24,25,27)/t13-,14-/m0/s1

የኢንቺ ቁልፍ፡

NCHUWRLOTSAFFN-KBPBESRZSA-N

ቁልፍ ቃል፡

2455427-91-3;CAS:2455427-91-3;CAS:2455427-91-3;AZD0780; AZD0780; AZD0780; EX-A6975; EX-A 6975; EXA6975; laroprovstatum; laroprovstat

መሟሟት; 

ማከማቻ፡ደረቅ, ጨለማ እና በ0 -4 ሴ ለአጭር ጊዜ (ከቀን እስከ ሳምንታት) ወይም -20 ሴ ለረጅም ጊዜ (ከወር እስከ አመታት).

መግለጫ፡-

PCSK9-IN-12 ሄትሮአሮማቲክ ውህድ ነው። PCSK9-IN-12 ከKd እሴት ጋር ለ PCSK9 አስገዳጅ ትስስር አለው።<200 nM. PCSK9-IN-12 ለኮሌስትሮል ሜታቦሊዝም ጥናት ሊያገለግል ይችላል።

ዓላማ፡ PCSK9