I-Tavapadon

Igama Lekhemikhali:

1,5-dimethyl-6-[2-methyl-4-[3-(trifluoromethyl)pyridin-2-yl]oxyphenyl]pyrimidine-2,4-dione

Ikhodi ye-SMILES:

O=C1NC(C(C)=C(C2=CC=C(OC3=NC=CC=C3C(F)(F)F)C=C2C)N1C)=O

Ikhodi ye-InChi:

I-InChI=1S/C19H16F3N3O3/c1-10-9-12(28-17-14(19(20,21)22)5-4-8-23-17 )6-7-13(10)15-11(2)16(26)24-18(27)25(15)3/h4-9H,1-3H3,(H,24,26,27)

I-InChi Key:

AKQXQLUNFKDZBN-UHFFFAOYSA-N

Igama elingukhiye:

1643489-24-0;CAS:1643489-24-0;CAS:1643489-24-0;Tavapadon; PF-6649751; PF 6649751; PF6649751; I-CVL-751; I-CVL 751; I-CVL751

Ukunyibilika:I-Soluble ku-DMSO

Isitoreji:Eyomile, emnyama futhi ku-0 - 4 C isikhathi esifushane (izinsuku ukuya emavikini) noma -20 C isikhathi eside (izinyanga kuya eminyakeni).

Incazelo:

I-Tavapadon, eyaziwa nangokuthi i-PF-6649751 kanye ne-CVL-751, iyingxenye ye-dopamine receptor agonist. Kungase kube usizo ekwelapheni isifo sikaParkinson kanye ne-Alzheimer's.

Okuqondiwe: I-Dopamine d1/d5 ama-agonists ayingxenye yamamukeli