I-SBP-7455

Igama Lekhemikhali:

I-N4-cyclopropyl-N2-(3,4-dimethoxyphenyl)-5-(trifluoromethyl)pyrimidine-2,4-diamine

Ikhodi ye-SMILES:

COC1=C(OC)C=CC(NC2=NC(NC3CC3)=C(C(F)(F)F)C=N2)=C1

Ikhodi ye-InChi:

I-InChI=1S/C16H17F3N4O2/c1-24-12-6-5-10(7-13(12)25-2)22-15-20-8-11(16(17,18)19)14(23- 15)21-9-3-4-9/h5-9H,3-4H2,1-2H3,(H2,20,21,22,23)

I-InChi Key:

BQROJYIEHOOQBY-UHFFFAOYSA-N

Igama elingukhiye:

1884222-74-5;CAS:1884222-74-5;CAS:1884222-74-5;SBP-7455;SBP7455;SBP 7455

Ukunyibilika:I-Soluble ku-DMSO

Isitoreji:Eyomile, emnyama futhi ku-0 - 4 C isikhathi esifushane (izinsuku ukuya emavikini) noma -20 C isikhathi eside (izinyanga kuya eminyakeni).

Incazelo:

I-SBP-7455 iyi-autophagy inhibitor esebenzayo, ephezulu, futhi esebenza ngomlomo i-ULK1/ULK2 autophagy inhibitor.

Ithagethi: ULK1/ULK2