MI

IKATI #	Igama Lomkhiqizo	Incazelo
I-CPD3218	I-BMS-955176	I-GSK3532795, eyaziwa nangokuthi i-BMS-955176, inamandla, iyasebenza ngomlomo, isizukulwane sesibili i-HIV-1 maturation inhibitor (MI) ethuthuke ngezivivinyo zomtholampilo zesigaba IIb. I-GSK3532795 ihlanganisa ukumbozwa okubanzi kwamagciwane e-polymorphic (EC50<15 nM ibheke kuphaneli ye-polymorphisms evamile emele u-96.5% wegciwane le-HIV-1 subtype B) elinephrofayili ye-pharmacokinetic ekahle ezinhlotsheni zangaphambi komtholampilo.