IKATI # | Igama Lomkhiqizo | Incazelo |
I-CPD100391 | I-SHP394 | |
I-CPD100390 | I-SHP389 (isisekelo samahhala) | |
I-CPD3242 | RMC-4550 | I-RMC-4550 iyisivimbeli esinamandla nesikhethayo se-SHP2. I-RMC-4550 ikhonjwe njengenhlanganisela yethuluzi lekhwalithi ephezulu yokufunda indima ye-SHP2 kubhayoloji yesimila, kokubili ku-vitro kanye ne-vivo kumagundane. I-SHP2 iyinodi yesiginali eguquguqukayo futhi ukuvimbela kwe-SHP2 kusebenza kahle ekuqondiseni kokubili ukuguqulwa komfula (okushayelwa yi-RTK) kanye nokwehla nomfula (okuncike ku-RAS-GTP) kumzila we-RAS-MAPK |