Obicetrapib;AMG-899;TA-8995

Igama Lekhemikhali:

4-((2-(3,5-bis(trifluoromethyl)benzyl)((2R,4S)-1-(ethoxycarbonyl)-2-ethyl-6-(trifluoromethyl) -1,2,3,4-tetrahydroquinolin -4-yl)amino)pyrimidin-5-yl)oxy)butanoic acid

Ikhodi ye-SMILES:

O=C(O)CCCOC1=CN=C(N(CC2=CC(C(F)(F)F)=CC(C(F)(F)F)=C2)[C@H]3C[C @@H](CC)N(C(OCC)=O)C4=C3C=C(C(F)(F)F)C=C4)N=C1

Ikhodi ye-InChi:

I-InChI=1S/C32H31F9N4O5/c1-3-22-14-26(24-13-19(30(33,34)35)7-8-25(24)45(22)29(48)49-4- 2)44(28-42-15-23(16-43-28)50-9-5-6-27(46)47)17-18-10-20(31(36,37)38)12- 21(11-18)32(39,40)41/h7-8,10-13,15-16,22,26H,3-6,9,14,17H2,1-2H3,(H,46,47 )/t22-,26+/m1/s1

I-InChi Key:

I-NRWORBQAOQVYBJ-GJZUVCINSA-N

Igama elingukhiye:

866399-87-3;CAS:866399-87-3;CAS:866399-87-3;Obicetrapib; I-AMG-899; I-AMG 899; I-AMG899; TA-8995; I-TA8995; TA 8995; I-DEZ-001; I-DEZ 001; I-DEZ001

Ukunyibilika:I-Soluble ku-DMSO

Isitoreji:Eyomile, emnyama futhi ku-0 - 4 C isikhathi esifushane (izinsuku ukuya emavikini) noma -20 C isikhathi eside (izinyanga kuya eminyakeni).

Incazelo:

I-Obicetrapib, eyaziwa nangokuthi i-AMG-899, TA-8995, ne-DEX-001, i-cholesteryl ester transfer protein (CETP) inhibitor.

Ithagethi: CETP