Ifebemtinib,BI 853520

Igama Lekhemikhali:

4--[[4-[(2,3-Dihydro-2-methyl-3-oxo-1H-isoindol-4-yl)oxy]-5-(trifluoromethyl)-2-pyrimidinyl]amino]-2-fluoro- 5-methoxy-N-(1-methyl-4-piperidinyl)benzamide

Ikhodi ye-SMILES:

O=C(NC1CCN(C)CC1)C2=CC(OC)=C(NC3=NC=C(C(F)(F)F)C(OC4=CC=CC(CN5C)=C4C5=O)= N3)C=C2F

Ikhodi ye-InChi:

I-InChI=1S/C28H28F4N6O4/c1-37-9-7-16(8-10-37)34-24(39)17-11-22(41-3)20(12-19(17)29)35- 27-33-13-18(28(30,3 1)32)25(36-27)42-21-6-4-5-15-14-38(2)26(40)23(15)21/h4-6,11-13,16H,7- 10,14H2,1-3H3,(H,34,39)(H,33,35,36)

I-InChi Key:

ULMMVBPTWVRPSI-UHFFFAOYSA-N

Igama elingukhiye:

1227948-82-4;CAS:1227948-82-4;CAS:1227948-82-4;Ifebemtinib;BI 853520

Ukunyibilika:Incibilika ku-DMSO, hhayi emanzini

Isitoreji:0 - 4 C isikhathi esifushane (izinsuku ukuya emavikini), noma -20 C isikhathi eside (izinyanga).

Incazelo:

I-Ifebemtinib (BI 853520) iyisivimbeli esinamandla se-focal adhesion kinase (FAK) esinomsebenzi womlomo.

Ithagethi: I-FAK Strong Inhibitor