I-Chenodeoxycholic Acid

Igama Lekhemikhali:

(R) -4-((3R,5S,7R,8R,9S,10S,13R,14S,17R)-3,7-dihydroxy-10,13-dimethylhexadecahydro-1H-cyclopenta[a]phenanthren-17-yl () i-pentanoic acid

Ikhodi ye-SMILES:

C[C@@H]([C@H]1CC[C@]2([H])[C@]3([H])[C@H](O)C[C@]4( [H])C[C@H](O)CC[C@]4(C)[C@@]3([H])CC[C@]12C)CCC(O)=O

Ikhodi ye-InChi:

I-InChI=1S/C24H40O4/c1-14(4-7-21(27)28)17-5-6-18-22-19(9-11-24(17,18)3)23(2)10- 8-16(25)12-15(23)13-20(22)26/h14-20,22,25-26H,4-13H2,1-3H3,(H,27,28)/t14-,15 +,16-,17-,18+,19+,20-,22+,23+,24-/m1/s1

I-InChi Key:

RUDATBOHQWOJDD-BSWAIDMHSA-N

Igama elingukhiye:

474-25-9, CAS:474-25-9, CAS:474-25-9，Chenodeoxycholic Acid, Anthropodeoxycholic acid,Anthropodesoxycholic acid,CCRIS 2195,Chendol,chenic acid; Chenix, Chenodeoxycholic acid, Chenodesoxycholic acid, Chenodiol, Gallodesoxycholic acid, NSC 657949, Xenbilox

Ukunyibilika:Incibilika ku-DMSO, hhayi emanzini

Isitoreji:Yomile, emnyama futhi ku-0 - 4 C isikhathi esifushane (izinsuku ukuya emavikini) noma -20 C isikhathi eside (izinyanga kuya eminyakeni)

Incazelo:

I-Chenodiol, eyaziwa nangokuthi i-Chenodeoxycholic Acid ne-chenocholic acid, iyi-bile acid. Kwenzeka njengento emhlophe eyikristalu engancibiliki emanzini kodwa encibilika otshwaleni ne-acetic acid, enephuzu lokuncibilika ku-165-167 °C. Usawoti wale carboxylic acid ubizwa ngokuthi i-chenodeoxycholates. I-Chenodeoxycholic acid isetshenziswe njengendlela yokwelapha ukuncibilikisa amatshe enyongo. I-Chenodeoxycholic acid ingasetshenziswa ekwelapheni i-cerebrotendineous xanthomatosis. Inkampani yase-Australia ye-biotechnology i-Giaconda ihlole ukwelashwa kwe-Hepatitis C ehlanganisa i-chenodeoxycholic acid ne-bezafibrate.

Ithagethi: I-FXR ye-nuclear receptor evuliwe