I-BN104

Igama Lekhemikhali:

(2-(6-(2-(4-cyclopropylpyrimidin-5-yl)-4-fluorophenoxy)-1,2,4-triazin-5-yl)-2,7-diazaspiro[3.5]nonan-7-yl )(1S,3aR,6aS)-octahydrocyclopenta[c]pyrrol-1-yl)methanone

Ikhodi ye-SMILES:

[H][C@@]12CCC[C@]1([H])[C@H](NC2)C(=O)N3CCC4(CN(C4)C5=C(OC6=CC=C(F) C=C6C7=CN=CN=C7C8CC8)N=NC=N5)CC3

Ikhodi ye-InChi:

1S/C31H35FN8O2/c32-21-6-7-25(23(12-21)24-14-33-17-35-26(24)19-4-5-19)42-29-28(36- 18-37-38-29)40-15-31(16-40)8-10-39(11-9-31)30(41)27-22-3-1-2-20(22)13- 34-27/h6-7,12,14,17-20,22,27,34H,1-5,8-11,13,15-16H2/t20-,22-,27-/m0/s1

I-InChi Key:

XDXAYPYOHXUEAM-CLHVYKLBSA-N

Igama elingukhiye:

2938995-50-5;CAS:2938995-50-5;CAS:2938995-50-5;BN-104;BN104;BN 104

Ukunyibilika: 

Isitoreji:Yomile, emnyama futhi ku-0 -4 C isikhathi esifushane (izinsuku ukuya emavikini) noma -20 C isikhathi eside (izinyanga kuya eminyakeni)

Incazelo:

I-BN-104 (BNM-1192) ingavimbela ukusebenzisana kwe-Menin MLL futhi ingasetshenziswa ocwaningweni lomdlavuza, njenge-acute myeloid leukemia.

Ithagethi: Menin-MLL