BI-3812

Igama Lekhemikhali:

1-(5-Chloro-4-((8-methoxy-1-methyl-3-(2-(methylamino)-2-oxoethoxy)-2-oxo-1,2-dihydroquinolin-6-yl)amino)pyrimidin -2-yl)-N,N-dimethylpiperidine-4-carboxamide

Ikhodi ye-SMILES:

O=C(C1CCN(C2=NC=C(Cl)C(NC3=CC4=C(N(C)C(C(OCC(NC)=O)=C4)=O)C(OC)=C3) =N2)CC1)N(C)C

Ikhodi ye-InChi:

I-InChI=1S/C26H32ClN7O5/c1-28-21(35)14-39-20-11-16-10-17(12-19(38-5)22(16)33(4)25(20)37) 30-23-18(27)13-29-26(31-23)34-8-6-15(7-9-34)24(36)32(2)3/h10-13,15H,6- 9,14H2,1-5H3,(H,28,35)(H,29,30,31)

I-InChi Key:

XCGYXEVLQIIEJH-UHFFFAOYSA-N

Igama elingukhiye:

BI-3812; BI 3812; BI3812

Ukunyibilika: 

Isitoreji: 

Incazelo:

I-BI-3812 iyisivimbeli esinamandla sokusebenzisana kwesizinda se-BTB/POZ se-BCL6 esinabacindezeli abambalwa abambalwa. Isebenza ngokuvimbela ukwakheka okuyinkimbinkimbi kwe-BCL6::Co-repressor.

Ithagethi: BCL6