I-BEC HCl

Igama Lekhemikhali:

(R)-2-amino-3-((2-boronoethyl)thio)propanoic acid hydrochloride

Ikhodi ye-SMILES:

N[C@@H](CSCCB(O)O)C(O)=O.[H]Cl

Ikhodi ye-InChi:

I-InChI=1S/C5H12BNO4S.ClH/c7-4(5(8)9)3-12-2-1-6(10)11;/h4,10-11H,1-3,7H2,(H,8, 9);1H/t4-;/m0./s1

I-InChi Key:

GHPYJLCQYMAXGG-WCCKRBBISA-N

Igama elingukhiye:

I-BEC HCl, 222638-67-7

Ukunyibilika:I-Soluble ku-DMSO

Isitoreji:0 - 4°C isikhathi esifushane (izinsuku ukuya emavikini), noma -20°C isikhathi eside (izinyanga)

Incazelo:

I-BEC, eyaziwa nangokuthi i-S-(2-boronoethyl)-L-cysteine, iyisivimbeli esibopha kancane futhi esiqhudelanayo se-Arginase II esine-Ki ka-0.31 μM (ph 7.5). I-BEC ithuthukisa ngokuphawulekayo ukukhululeka okungancikile kwe-PEnile corpus canvernosum yemisipha ebushelelezi ku-vitro ekugxilweni okuphakathi kuka-0.1-1.0 mM. I-S-(2-boronoethyl) -L-cysteine ​​​​ibophezela ku-arginase njenge-analogue yesimo soguquko futhi ithuthukise ukukhululeka kwemisipha ebushelelezi ku-penile corpus cavernosum yomuntu.

Ithagethi: Arginase