AZD0780;EX-A6975;laroprovstatum; i-laroprovstat
Imininingwane Yomkhiqizo
Omaka bomkhiqizo
Usayizi Wephakethe | Ukutholakala | Intengo (USD) |
Igama Lekhemikhali:
6'-(((1S,3S)-3-((5-(difluoromethoxy)pyrimidin-2-yl)amino)cyclopentyl)amino)-2H-[1,3'-bipyridin]-2-one
Ikhodi ye-SMILES:
O=C1N(C=CC=C1)C2=CN=C(N[C@@H]3C[C@H](CC3)NC4=NC=C(OC(F)F)C=N4)C= C2
Ikhodi ye-InChi:
I-InChI=1S/C20H20F2N6O2/c21-19(22)30-16-11-24-20(25-12-16)27-14-5-4-13(9-14)26-17-7-6- 15(10-23-17)28-8-2-1-3-18(28)29/h1-3,6-8,10-14,19H,4-5,9H2,(H,23,26 )(H,24,25,27)/t13-,14-/m0/s1
I-InChi Key:
NCHUWRLOTSAFFN-KBPBESRZSA-N
Igama elingukhiye:
2455427-91-3;CAS:2455427-91-3;CAS:2455427-91-3;AZD0780; I-AZD0780; I-AZD0780; I-EX-A6975; EX-A 6975; I-EXA6975; i-laroprovstatum; i-laroprovstat
Ukunyibilika:
Isitoreji:Yomile, emnyama futhi ku-0 -4 C isikhathi esifushane (izinsuku ukuya emavikini) noma -20 C isikhathi eside (izinyanga kuya eminyakeni).
Incazelo:
I-PCSK9-IN-12 iyinhlanganisela ye-heteroaromatic. I-PCSK9-IN-12 inobudlelwane obubophezelayo be-PCSK9 ngevelu ye-Kd<200 nM. I-PCSK9-IN-12 ingasetshenziselwa ucwaningo lwe-cholesterol metabolism.
Ithagethi: PCSK9