DEL-22379
Iinkcukacha zeMveliso
Iithegi zeMveliso
| Ubungakanani bePakethi | Ubukho | Ixabiso (USD) |
| 100mg | Ikhona evenkileni | 350 |
| 250mg | Ikhona evenkileni | 600 |
| 1g | Ikhona evenkileni | 1200 |
| Iisayizi ezininzi | Fumana iiQuotes | Fumana iiQuotes |
Igama leMchiza:
(Z)-N-(3-((5-methoxy-1H-indol-3-yl)methylene)-2-oxoindolin-5-yl)-3-(piperidin-1-yl)propanamide
Ikhowudi yoncumo:
O=C(NC1=CC2=C(NC(/C2=C/C3=CNC4=C3C=C(OC)C=C4)=O)C=C1)CCN5CCCCC5
Ikhowudi ye-InChi:
InChI=1S/C26H28N4O3/c1-33-19-6-8-23-20(15-19)17(16-27-23)13-22-21-14-18(5-7-24(21) 29-26 (22) 32)28-25(31)9-12-30-10-3-2-4-11-30/h5-8,13-16,27H,2-4,9-12H2,1H3,(H,28 ,31)(H,29,32)/b22-13+
Isitshixo se-InChi:
I-INQUULXCZAKMS-LPYMAVHISA-N
Igama elingundoqo:
DEL-22379, DEL22379, DEL 22379, 181223-80-3
Ukunyibilika:Inyibilika kwi-DMSO
Ugcino:0 - 4°C ixesha elifutshane (iintsuku ukuya kwiiveki), okanye -20°C ixesha elide (iinyanga)
Inkcazo:
I-DEL-22379 inamandla kwaye ikhetha i-ERK Dimerization inhibitor. I-DEL-22379 inqanda i-ERK Dimerization ngaphandle kokuchaphazela i-ERK phosphorylation, ikhusela i-tumorigenesis eqhutywa yi-RAS-ERK indlela ye-oncogenes. Phantse i-50% yeengxaki zomntu zibonisa ukubonakaliswa okungalawulwayo kwe-RAS-ERK; ukuthintela sisicwangciso esisebenzayo songenelelo lwe-antineoplastic.
Ekujoliswe kuko: ERK
