AZD0780;EX-A6975;laroprovstatum; laroprovstat

Igama leMchiza:

6'-(((1S,3S)-3-((5-(difluoromethoxy)pyrimidin-2-yl)amino)cyclopentyl)amino)-2H-[1,3'-bipyridin]-2-enye

Ikhowudi yoncumo:

O=C1N(C=CC=C1)C2=CN=C(N[C@@H]3C[C@H](CC3)NC4=NC=C(OC(F)F)C=N4)C= C2

Ikhowudi ye-InChi:

InChI=1S/C20H20F2N6O2/c21-19(22)30-16-11-24-20(25-12-16)27-14-5-4-13(9-14)26-17-7-6- 15(10 -23-17)28-8-2-1-3-18(28)29/h1-3,6-8,10-14,19H,4-5,9H2,(H,23,26)(H ,24,25,27)/t13-,14-/m0/s1

Isitshixo se-InChi:

NCHUWRLOTSAFFN-KBPBESRZSA-N

Igama elingundoqo:

2455427-91-3;CAS:2455427-91-3;CAS:2455427-91-3;AZD0780; I-AZD0780; I-AZD0780; EX-A6975; EX-A 6975; EXA6975; laroprovstatum; laroprovstat

Ukunyibilika: 

Ugcino:Yomile, emnyama kunye ne-0 -4 C kwixesha elifutshane (iintsuku ukuya kwiiveki) okanye -20 C ixesha elide (iinyanga ukuya kwiminyaka).

Inkcazo:

I-PCSK9-IN-12 yi-hetermatic compound. I-PCSK9-IN-12 inobudlelwane obubophelelayo be-PCSK9 ngexabiso le-Kd<200 nM. I-PCSK9-IN-12 ingasetyenziselwa isifundo se-cholesterol metabolism.

Ithagethi: PCSK9