GDC-0077

Himiki ady:

(S) -2 - (((2) ] oksazepin-9 ýyl) amin) propanamid

SMILES kody:

C [C @@ H] (C (N) = O) NC1 = CC = C (C2 = NC (N3 [C @ H] (C (F) F) COC3 = O) = CN2CCO4) C4 = C1

InChi kody:

InChI = 1S / C18H19F2N5O4 / c1-9 (16 (21) 26) 22-10-2-3-11-13 (6-10) 28-5-4-24-7-14 (23-17 (11)) 24) 25-12 (15 (19) 20) 8-29-18 (25) 27 / h2-3,6-7,9,12,15,22H, 4-5,8H2,1H3, (H2,21 , 26) / t9-, 12- / m0 / s1

InChi açary:

SGEUNORSOZVTOL-CABZTGNLSA-N

Açar söz:

GDC-0077; GDC 0077; GDC0077

Çözüw:DMSO

Saklama: 

Düşündiriş:

GDC-0077, antineoplastiki işjeňligi bolan dilden elýeterli PI3K inhibitorydyr. GDC-0077 WO 2017001645 A1 patentinden, I formuladan alyndy.

Maksat: PI3K