Vardenafil
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Lebitso la lik'hemik'hale:
2-(2-ethoxy-5-((4-ethylpiperazin-1-yl)sulfonyl)phenyl)-5-methyl-7-propyl-3,5,6,7-tetrahydro-4H-5l4-imidazo[1, 5-a [1,3,5]triazin-4-one
SMILES Khouto:
O=C(NC(C1=CC(S(=O)(N2CCN(CC)CC2)=O)=CC=C1OCC)=N3)[N]4(C)C3=CN(CCC)C4
Khoutu ea InChi:
InChI=1S/C23H35N6O4S/c1-5-10-27-16-21-24-22(25-23(30)29(21,4)17-27)19-15-18(8-9-20( 19) 33-7-3)34(31,32)28-13-11-26(6-2)12-14-28/h8-9,15-16H,5-7,10-14,17H2,1- 4H3,(H,24,25,30)
InChi Key:
UWRWYSQUBZFWPU-UHFFFAOYSA-N
Keyword:
Vardenafil, Levitra, Staxyn, Vivanza, BAY 38-9456, BAY-38-9456, BAY38-9456, 224785-90-4
Sollubility:E qhibiliha ka DMSO
Polokelo:0 - 4 ° C bakeng sa nako e khutšoanyane (matsatsi ho isa libeke), kapa -20 ° C bakeng sa nako e telele (likhoeli)
Tlhaloso:
Vardenafil, e tsejoang hape e le BAY 38-9456, ke PDE5 inhibitor e sebelisetsoang ho phekola ho se sebetse ha erectile. Lipontšo tsa Vardenafil le li-contra-indication li tšoana le tse ling tsa PDE5 inhibitors; e amana haufi-ufi le ts'ebetso ea sildenafil citrate (Viagra) le tadalafil (Cialis). Phapang pakeng tsa molek'hule ea vardenafil le sildenafil citrate ke boemo ba athomo ea nitrogen le phetoho ea sildenafil's piperazine ring methyl group ho sehlopha sa ethyl. Tadalafil e fapane ka tsela e fapaneng le sildenafil le vardenafil. Nako e batlang e le khutšoanyane ea Vardenafil e bapisoa le nako e telele ho feta sildenafil.
Sepheo: PDE5