TNG-908; EX-A7872

Lebitso la lik'hemik'hale:

N-(6-amino-5-methylpyridin-3-yl)-2-((2R,5S)-2-(benzo[d]thiazol-5-yl)-5-methylpiperidin-1-yl)-2- oxoacetamide

SMILES Khouto:

CC1=CC(NC(C(N2[C@@H])(C3=CC=C(SC=N4)C4=C3)CC[C@@H](C2)C)=O)=O)=CN =C1N

Khoutu ea InChi:

InChI=1S/C21H23N5O2S/c1-12-3-5-17(14-4-6-18-16(8-14)24-11-29-18)26(10-12)21(28)20( 27)25-15-7-13(2)19(22)23-9-15/h4,6-9,11-12,17H,3,5,10H2,1-2H3,(H2,22,23 )(H,25,27)/t12-,17+/m0/s1

InChi Key:

NXXBDYHMHHINFC-YVEFUNNKSA-N

Keyword:

2760481-53-4;CAS:2760481-53-4;CAS:2760481-53-4;TNG908;TNG-908;TNG 908;EX-A7872;

Sollubility: 

Polokelo:E omme, e lefifi le ho 0 -4 C bakeng sa nako e khutšoanyane (matsatsi ho isa ho libeke) kapa -20 C nako e telele (likhoeli ho isa ho lilemo).

Tlhaloso:

TNG908 ke MTAP synergistic PRMT5 inhibitor.

Sepheo: PRMT5