Chenodeoxycholic acid

Lebitso la lik'hemik'hale:

(R) -4-((3R,5S,7R,8R,9S,10S,13R,14S,17R)-3,7-dihydroxy-10,13-dimethylhexadecahydro-1H-cyclopenta[a]phenanthren-17-yl "pentanoic acid".

SMILES Khouto:

C[C@@H]([C@H]1CC[C@]2([H])[C@]3([H])[C@H](O)C[C@]4( [H])C[C@H](O)CC[C@]4(C)[C@@]3([H])CC[C@]12C)CCC(O)=O

Khoutu ea InChi:

InChI=1S/C24H40O4/c1-14(4-7-21(27)28)17-5-6-18-22-19(9-11-24(17,18)3)23(2)10- 8-16(25)12-15(23)13-20(22)26/h14-20,22,25-26H,4-13H2,1-3H3,(H,27,28)/t14-,15 +,16-,17-,18+,19+,20-,22+,23+,24-/m1/s1

InChi Key:

RUDATBOHQWOJDD-BSWAIDMHSA-N

Keyword:

474-25-9, CAS: 474-25-9, CAS: 474-25-9，Chenodeoxycholic Acid, Anthropodeoxycholic acid, Anthropodesoxycholic acid, CCRIS 2195，Chendol,chenic acid; Chenix, Chenodeoxycholic acid, Chenodesoxycholic acid, Chenodiol, Gallodesoxycholic acid, NSC 657949, Xenbilox

Sollubility:E qhibiliha ka DMSO, eseng ka metsing

Polokelo:E omme, e lefifi le ho 0 - 4 C bakeng sa nako e khutšoanyane (matsatsi ho isa ho libeke) kapa -20 C ka nako e telele (likhoeli ho isa ho lilemo)

Tlhaloso:

Chenodiol, e tsejoang hape e le Chenodeoxycholic Acid le chenocholic acid, ke bile acid. E hlaha e le ntho e tšoeu ea kristale e ke keng ea qhibiliha ka metsing empa e qhibiliha ka joala le asiti ea acetic, e nang le ntlha ea ho qhibiliha ho 165-167 ° C. Matsoai a acid ena ea carboxylic a bitsoa chenodeoxycholates. Chenodeoxycholic acid e 'nile ea sebelisoa e le phekolo ea meriana ho qhala majoe a majoe. Chenodeoxycholic acid e ka sebelisoa ho phekola cerebrotendineous xanthomatosis. Khampani ea Australia ea biotechnology Giaconda e lekile kalafo bakeng sa tšoaetso ea Hepatitis C e kopanyang chenodeoxycholic acid le bezafibrate.

Sepheo: Sesebelisoa sa nuclear se kentsoeng FXR