GSK2330672; linerixibat

GSK2330672; linerixibat
  • Lebitso:Pentanedioic acid, 3-(((3R,5R)-3-butyl-3-ethyl-2,3,4,5-tetrahydro-7-methoxy-1,1-dioxido-5-phenyl-1,4- benzothiazepin-8-yl)methyl)amino)-
  • Nomoro ea lethathamo:CPD107582
  • Nomoro ea CAS:1345982-69-5
  • Boima ba Molek'hule:546.68
  • Foromo ea Lik'hemik'hale:C28 H38 N2 O7 S
  • Bakeng sa lipatlisiso tsa saense feela, eseng bakeng sa bakuli.

    Lintlha tsa Sehlahisoa

    Li-tag tsa Sehlahisoa

    Boholo ba Pakete Ho fumaneha Theko (USD)
    0.1G E teng thepeng e teng ka lebenkeleng 570
    0.5G E teng thepeng e teng ka lebenkeleng 980
    1G E teng thepeng e teng ka lebenkeleng 1320

    Lebitso la lik'hemik'hale:

    Pentanedioic acid, 3-(((3R,5R)-3-butyl-3-ethyl-2,3,4,5-tetrahydro-7-methoxy-1,1-dioxido-5-phenyl-1,4- benzothiazepin-8-yl)methyl)amino)-

    SMILES Khouto:

    O=C(O)CC(NCC1=C(OC)C=C(C2=C1)[C@@H](C3=CC=CC=C3)N[C@](CC)(CCCC)CS2( =O)=O)CC(O)=O

    Khoutu ea InChi:

    InChI=1S/C28H38N2O7S/c1-4-6-12-28(5-2)18-38(35,36)24-13-20(17-29-21(14-25(31)32)15- 26(33)34)23(37-3)16-22(24)2 7(30-28)19-10-8-7-9-11-19/h7-11,13,16,21,27,29-30H,4-6,12,14-15,17-18H2, 1-3H3,(H,31,32)(H,33,34)/t27-,28-/m1/s1

    InChi Key:

    CZGVOBIGEBDYTP-VSGBNLITSA-N

    Keyword:

    1345982-69-5;CAS:1345982-69-5;CAS:1345982-69-5;GSK-2330672; GSK 2330672; GSK2330672; linerixibat

    Sollubility:E qhibiliha ka DMSO

    Polokelo:E omme, e lefifi le ho 0 - 4 C bakeng sa nako e khutšoanyane (matsatsi ho isa ho libeke) kapa -20 C bakeng sa nako e telele (likhoeli ho isa ho lilemo).

    Tlhaloso:

    Linerixibat (GSK2330672) ke inhibitor e sebetsang hantle haholo, e sa monyeheng, ebile e sebetsa ka molomo ka holimo ho sodium e itšetlehileng ka bile acid transporter (ASBT) inhibitor.

    Sepheo: ASBT




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