GDC-0326
Lintlha tsa Sehlahisoa
Li-tag tsa Sehlahisoa
| Boholo ba Pakete | Ho fumaneha | Theko (USD) |
| 1g | E teng thepeng e teng ka lebenkeleng | 1800 |
| Boholo bo Eketsehileng | Fumana Litlhaloso | Fumana Litlhaloso |
Lebitso la lik'hemik'hale:
(S)-2-((2-(1-isopropyl-1H-1,2,4-triazol-5-yl)-5,6-dihydrobenzo[f]imidazo[1,2-d][1,4 ]oxazepin-9-yl)oxy)propanamide
SMILES Khouto:
C[C@H](OC1=CC=C2C3=NC(C4=NC=NN4C(C)C)=CN3CCOC2=C1)C(N)=O
Khoutu ea InChi:
InChI=1S/C19H22N6O3/c1-11(2)25-19(21-10-22-25)15-9-24-6-7-27-16-8-13(28-12(3)17( 20)26)4-5-14(16)18(24)23-15/h4-5,8-12H,6-7H2,1-3H3,(H2,20,26)/t12-/m0/s1
InChi Key:
SIKYDKLGPWRPMZ-LBPRGKRZSA-N
Keyword:
GDC-0326, GDC0326, GDC 0326, 1282514-88-8
Sollubility:E qhibiliha ka DMSO
Polokelo:0 - 4 ° C bakeng sa nako e khutšoanyane (matsatsi ho isa libeke), kapa -20 ° C bakeng sa nako e telele (likhoeli)
Tlhaloso:
GDC-0326 ke inhibitor e matla le e khethang ea α-Isoform ea Phosphoinositide 3-Kinase (PI3Kalpha inhibitor). GDC-0326 e fihlella boemo bo phahameng haholo ba khetho ho feta li-kinase tse ling. GDC-0326 e na le plasma e tlase ea CL ho motho. Ka har'a lelapa la PI3 kinase, ho na le li-isoform tse 'ne tsa sehlopha sa I PI3K (α, β, δ, le γ). Har'a li-isoform tsena, PI3Kα ke eona e amanang haholo le mofetše.
Sepheo: PI3K
