BAY-1895344
Lintlha tsa Sehlahisoa
Li-tag tsa Sehlahisoa
| Boholo ba Pakete | Ho fumaneha | Theko (USD) |
| 10mg | E teng thepeng e teng ka lebenkeleng | 210 |
| 100mg | E teng thepeng e teng ka lebenkeleng | 480 |
| 1g | E teng thepeng e teng ka lebenkeleng | 950 |
Lebitso la lik'hemik'hale:
(R)-3-methyl-4-(4-(1-methyl-1H-pyrazol-5-yl)-8-(1H-pyrazol-5-yl)-1,7-naphthyridin-2-yl)morpholine
SMILES Khouto:
CN1N=CC=C1C2=CC(N3[C@H](C)COCC3)=NC4=C(C5=CC=NN5)N=CC=C24.[H]Cl
Khoutu ea InChi:
InChI=1S/C20H21N7O.ClH/c1-13-12-28-10-9-27(13)18-11-15(17-5-8-23-26(17)2)14-3-6- 21-2 0(19(14)24-18)16-4-7-22-25-16;/h3-8,11,13H,9-10,12H2,1-2H3,(H,22,25);1H /t13-;/m1./s1
InChi Key:
KWQNBYGUBHMRPY-BTQNPOSSSA-N
Keyword:
1876467-74-1;CAS:1876467-74-1;CAS:1876467-74-1;BAY-1895344, BAY1895344, BAY 1895344
Sollubility:E qhibiliha ka DMSO
Polokelo:0 - 4 ° C bakeng sa nako e khutšoanyane (matsatsi ho isa libeke), kapa -20 ° C bakeng sa nako e telele (likhoeli).
Tlhaloso:
BAY-1895344 ke inhibitor e khethiloeng ea ATR (ataxia-telangiectasia le Rad3 e amanang le protheine) e thibelang ho ata ha mefuta e mengata ea lisele tsa lisele tsa batho (median IC50 = 78 nM). BAY-1895344 e etselitsoe kalafo ea bakuli ba nang le lihlahala tse tiileng tse tsoetseng pele le li-lymphomas, 'me e ntse e lekoa tekong ea bongaka ea mohato oa I ea polokeho le mamello ho bakuli ba mofetše.
Sepheo: ATR