AZD0780;EX-A6975;laroprovstatum; laroprovstat

Lebitso la lik'hemik'hale:

6'-(((1S,3S)-3-((5-(difluoromethoxy)pyrimidin-2-yl)amino)cyclopentyl)amino)-2H-[1,3'-bipyridin] -2-one

SMILES Khouto:

O=C1N(C=CC=C1)C2=CN=C(N[C@@H]3C[C@H](CC3)NC4=NC=C(OC(F)F)C=N4)C= C2

Khoutu ea InChi:

InChI=1S/C20H20F2N6O2/c21-19(22)30-16-11-24-20(25-12-16)27-14-5-4-13(9-14)26-17-7-6- 15(10-23-17)28-8-2-1-3-18(28)29/h1-3,6-8,10-14,19H,4-5,9H2,(H,23,26 )(H,24,25,27)/t13-,14-/m0/s1

InChi Key:

NCHUWRLOTSAFFN-KBPBESRZSA-N

Keyword:

2455427-91-3;CAS:2455427-91-3;CAS:2455427-91-3;AZD0780; AZD0780; AZD0780; EX-A6975; EX-A 6975; EXA6975; laroprovstatum; laroprovstat

Sollubility: 

Polokelo:E omme, e lefifi le ho 0 -4 C bakeng sa nako e khutšoanyane (matsatsi ho isa ho libeke) kapa -20 C nako e telele (likhoeli ho isa ho lilemo).

Tlhaloso:

PCSK9-IN-12 ke motsoako oa hetermatic. PCSK9-IN-12 e na le kamano e tlamang bakeng sa PCSK9 e nang le boleng ba Kd<200 nM. PCSK9-IN-12 e ka sebelisoa ho ithuta ka metabolism ea k'holeseterole.

Sepheo: PCSK9