Divarasib,GDC 6036

Divarasib,GDC 6036
  • Lebitso:1-((S)-4-(7-((R)-6-amino-4-methyl-3-(trifluoromethyl)pyridin-2-yl)-6-chloro-8-fluoro-2-(((( S)-1-methylpyrrolidin-2-yl)methoxy)quinazolin-4-yl)-3-methylpiperazin-1-yl)prop-2-en-1-one
  • Nomoro ea lethathamo:CPD112857
  • Nomoro ea CAS:2417987-45-0
  • Boima ba Molek'hule:622.06
  • Foromo ea Lik'hemik'hale:C29 H32 Cl F4 N7 O2
  • Bakeng sa lipatlisiso tsa saense feela, eseng bakeng sa bakuli.

    Lintlha tsa Sehlahisoa

    Li-tag tsa Sehlahisoa

    Boholo ba Pakete Ho fumaneha Theko (USD)
    0.1G E teng thepeng e teng ka lebenkeleng 550
    0.5G E teng thepeng e teng ka lebenkeleng 860
    1G E teng thepeng e teng ka lebenkeleng 1250

    Lebitso la lik'hemik'hale:

    1-((S)-4-(7-((R)-6-amino-4-methyl-3-(trifluoromethyl)pyridin-2-yl)-6-chloro-8-fluoro-2-(((( S)-1-methylpyrrolidin-2-yl)methoxy)quinazolin-4-yl)-3-methylpiperazin-1-yl)prop-2-en-1-one

    SMILES Khouto:

    NC1=N[C@]([C@]2=C(C=C3C(N=C(N=C3N4[C@H](CN(CC4)C(C=C)=O)C)OC[ C@H]5N(CCC5)C)=C2F)Cl)=C(C(C)=C1)C(F)(F)F

    Khoutu ea InChi:

    InChI=1S/C29H32ClF4N7O2/c1-5-21(42)40-9-10-41(16(3)13-40)27-18-12-19(30)22(26-23(29(32,) 33)34)15(2)11-20(35)36-26)24(31)25(18)37-28(38-27)43-14-17-7-6-8-39(17) 4/h5,11-12,16-17H,1,6-10,13-14H2,2-4H3,(H2,35,36)

    InChi Key:

    ZRBPIAWWRPFDPY-UHFFFAOYSA-N

    Keyword:

    2417987-45-0;CAS:2417987-45-0;CAS:2417987-45-0;Divarasib;GDC 6036

    Sollubility:SolubilityTo be ikemiselitse

    Polokelo:E omme, e lefifi le ho 0 - 4 C bakeng sa nako e khutšoanyane (matsatsi ho isa ho libeke) kapa -20 C bakeng sa nako e telele (likhoeli ho isa ho lilemo).

    Tlhaloso:

    Divarasib (GDC-6036) ke KRAS G12C inhibitor e nang le bioavailability ea molomo le khetho.

    Sepheo: KRAS G12C inhibitor




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