Vactosertib
Faahfaahinta Alaabta
Tags Product
| Cabbirka Xidhmada | Helitaanka | Qiimaha (USD) |
| 500mg | In Stock | 800 |
| 1g | In Stock | 1300 |
| 5g | In Stock | 3800 |
| Cabiro badan | Hel Xigasho | Hel Xigasho |
Magaca Kiimikada:
N-(4-([1,2,4]triazolo [1,5-a] pyridin-6-yl)-5-(6-methylpyridin-2-yl)-1H-imidazol-2-yl)methyl -2-fluoroaniline
Koodhka dhoola cadeynta:
FC1=CC=CC=CC=C1NCC2=NC(C3=CN4C(C=C3)=NC=N4)=C(C5=NC(C)=CC=C5)N2
Koodhka InChi:
InChi=1S/C22H18FN7/c1-14-5-4-8-18(27-14)22-21(15-9-10-20-25-13-26-30(20)12-15)28- 19 (29-22)11-24-17-7-3-2-6-16(17)23/h2-10,12-13,24H,11H2,1H3,(H,28,29)
Furaha InChi:
FJCDSQATIJKQKA-UHFFFAOYSA-N
Ereyga muhiimka ah:
Vactosertib, EW-7197, EW7197, EW 7197, 1352608-82-2
Xalka:Ku milmay DMSO
Kaydinta:0 - 4°C muddo gaaban (maalmo ilaa toddobaadyo), ama -20°C muddo dheer (bilo)
Sharaxaad:
Vactosertib, oo sidoo kale loo yaqaan EW-7197 waa ka hortag awood leh oo ALK5 ah. EW-7197 waxay muujisay firfircoonida firfircoonida anti-metastatic vivo, taas oo muujinaysa suurtagalnimada isticmaalka daaweynta kansarka ka hortagga. EW-7197 waxay joojisaa calaamadaha TGF-β/Smad. EW-7197 waxay baabi'isaa TGF-β1 guuritaanka unugyada burooyinka iyo duulaanka. EW-7197 waxay ka hortagtaa kansarka naasaha sambabada EW-7197 waxay joojisaa dheef-shiid kiimikaadka waxayna wanaajisaa waxqabadka cytotoxic T lymphocytes (CTLs) ee 4T1 jiirarka lafaha lafaha.
Ujeedka: ALK
