STING agonist-4

Magaca Kiimikada:

1,1'-(butane-1,4-diyl)bis(2- (1-ethyl-3-methyl-1H-pyrazole-5-carboxamido)-1H-benzo[d]imidazole-5-carboxamide)

Koodhka dhoola cadeynta:

O=C(C1=CC=C2N(CCCCN3C(NC(C4=CC(C)=NN4CC)=O)=NC5=CC(C(N)=O)=CC=C35 (C)=NN6CC)=O)=NC2=C1)N

Koodhka InChi:

InChi=1S/C34H38N12O4/c1-5-45-27(15-19(3)41-45)31(49)39-33-37-23-17-21(29(35)47)9-11- 25(23)43(33)13-7-8-14-44-26-12-10-22(30(36)48)18-24(26)38-34(44)40-32(50) 28-16-20 (4)42-46(28)6-2/h9-12,15-18H,5-8,13-14H2,1-4H3,(H2,35,47)(H2,36, 48) (H,37,39,49)(H,38,40,50)

Furaha InChi:

ICZSAXDKFXTSGL-UHFFFAOYSA-N

Ereyga muhiimka ah:

Xalka: 

Kaydinta: 

Sharaxaad:

STING agonist-4 waa kiciyeyaasha Interferon Genes (STING) agonist receptor agonist oo leh joogto ah inhibitory (IC50) ee 20 nM. STING agonist-4 waa laba asymmetry-xiriira amidobenzimidazole (ABZI) - xarun ku salaysan si loo abuuro ABZI (diABZI) oo ku xidhan STING iyo shaqada gacanta

Ujeedka: STING