diABZI STING agonist-1

Magaca Kiimikada:

(E) -1- (4- (5-carbamoyl-2---1-ethyl-3-methyl-1H-pyrazole-5-carboxamido) -7- (3-morpholinopropoxy) -1H-benzo[d] imidazole -1-yl)laakin-2-en-1-yl)-2-(1-ethyl-3-methyl-1H-pyrazole-5-carboxamido)-7-methoxy-1H-benzo[d]imidazole-5- carboxamide

Koodhka dhoola cadeynta:

O=C(N)C1=CC(N=C(NC(C2=CC(C)=NN2CC)=O)N3C/C=C/CN4C(NC(C5=CC(C)=NN5CC)=O =NC6=C4C(OCCCN7CCOCC7)=CC(C(N)=O)=C6=C3C(OC)=C1

Koodhka InChi:

InChi=1S/C42H51N13O7/c1-6-54-31(19-25(3)49-54)39(58)47-41-45-29-21-27(37(43) 56)23-33(60-5)35(29)52(41)12-8-9-13-53-36-30(46-42(53)48-40(59)32-20-26 (4) 50-55(32)7-2)22-28(38 (44)57)24-34(36)62-16-10-11-51-14-17-61-18-15-51/h8- 9, 19-24H,6-7,10-18H2,1-5H3,(H2,43,56)(H2,44,57)(H,45,47,58)(H,46,48,59)/b9 -8+

Furaha InChi:

JGLMVXWAHNTPRF-CMDGGOBGSA-N

Ereyga muhiimka ah:

Xalka: 

Kaydinta: 

Sharaxaad:

diABZI STING agonist-1 waa kiciyeyaasha xulashada ee hiddo-wadaha interferon (STING) agonist receptor agonist, oo leh EC50s ee 130, 186 nM dadka iyo jiirka, siday u kala horreeyaan.

Ujeedka: STING