STING agonist-3
Faahfaahinta Alaabta
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Cabbirka Xidhmada | Helitaanka | Qiimaha (USD) |
Magaca Kiimikada:
(E)-1-(4- (5-carbamoyl-2-------laakin-2- en-1-yl)-2-(1-ethyl-3-methyl-1H-pyrazole-5-carboxamido)-7- (3-hydroxypropoxy) -1H-benzo[d] imidazole-5-carboxamide
Koodhka dhoola cadeynta:
O=C(N)C1=CC=C(N(C(NC(C2=CC(C)=NN2CC)=O)=N3)C/C=C/CN4C5=C(N=C4NC(C6=CC) (C)=NN6CC=O)C=C(C(N)=O)C=C5OCCCO)C3=C1
Koodhka InChi:
InChi=1S/C37H42N12O6/c1-5-48-28(16-21(3)44-48)34(53)42-36-40-25-18-23(32(38)51)10-11- 27(25)46(36)12-7-8-13-47-31-26(19-24(33(39)52)20-30(31)55-15-9-14-50)41- 37(47)43-35(54)29-17-22(4)45-49(29)6-2/h7-8,10-11,16-20,50H,5-6,9,12- 15H2,1-4H3,(H2,38,51)(H2,39,52)(H,40,42,53)(H,41,43,54)/b8-7+
Furaha InChi:
VHCDRDBBENBVEK-BQYQJAHWSA-N
Ereyga muhiimka ah:
Xalka:
Kaydinta:
Sharaxaad:
STING agonist-3, oo laga soosaaray patent WO2017175147A1 (tusaale 10), waa xulashada iyo non-nucleotide yar-molecule STING agonist leh pEC50 iyo pIC50 ee 7.5 iyo 9.5, siday u kala horreeyaan. STING agonist-3 waxay leedahay saameyn joogto ah oo ka hortagga burooyinka iyo awood weyn oo lagu wanaajiyo daaweynta kansarka
Ujeedka: STING