ND-630
Faahfaahinta Alaabta
Tags Product
| Cabbirka Xidhmada | Helitaanka | Qiimaha (USD) |
| 10mg | In stock | 300 |
| 50mg | In stock | 500 |
| 100mg | In stock | 800 |
| Cabiro badan | Hel Xigasho | Hel Xigasho |
Magaca Kiimikada:
(R) -2- (1- (2--methoxyphenyl) -2- ((tetrahydro-2H-pyran-4-yl) oxy) ethyl -5-methyl-6- (oxazol-2-yl) -2,4-dioxo-1,2-dihydrothieno[2,3-d]pyrimidin-3(4H)-yl)-2-methylpropanamide
Koodhka dhoola cadeynta:
O=C(N)C(C)(C)N(C(N(C[C@@H])(C1=CC=CC=C1OC)OC2CCOCC2)C3=C4C(C)=C(C5=NC= CO5)S3)=O)C4=O
Koodhka InChi:
InChi=1S/C28H31N3O8S/c1-16-21-24(32)31(28(2,3)26(33)34)27(35)30(25(21)40-22(16)23-29- 11-14-38-23)15-20 (39-17-9-12-37-13-10-17)18-7-5-6-8-19(18)36-4/h5-8, 11,14,17,20H,9-10,12-13,15H2,1-4H3,(H,33,34)/t20-/m0/s1
Furaha InChi:
ZZWWXIBKLBMSCS-FQEVSTJZSA-N
Ereyga muhiimka ah:
ND-630, ND630, ND 630, GS-0976, GS0976, GS 0976, NDI-010976, NDI010976, NDI 010976, Firsocostat, 1434635-54-7
Xalka:Ku milmay DMSO
Kaydinta:0 - 4°C muddo gaaban (maalmo ilaa toddobaadyo), ama -20°C muddo dheer (bilo).
Sharaxaad:
ND-630 waxay joojisaa hACC1 (IC50=2.1±0.2 nM) iyo hACC2 (IC50=6.1±0.8 nM). Ka-hortagga waa la rogi karaa oo si gaar ah ayey u tahay ACC. ND-630 waxay joojisaa dhaqdhaqaaqa ACC iyada oo la falgasha gudaha phosphopeptide-aqbalaha iyo kala-soocida goobta enzyme si looga hortago dimerization. ND-630 waxay joojisaa isku-darka aashitada dufanka leh ee EC50 ee 66 nM ee unugyada HepG2 iyada oo aan la beddelin tirada guud ee unugyada, xoojinta borotiinka gacanta, iyo ku daridda acetate ee kolestaroolka[1].
Ujeedka: ACC
