BLU-667
Faahfaahinta Alaabta
Tags Product
Cabbirka Xidhmada | Helitaanka | Qiimaha (USD) |
Magaca Kiimikada:
(1s, 4R)-N-((S)-1- (4--fluoro-1H-pyrasol-1-yl) phenyl) -1-methoxy-4- (4-methyl-6-). (5-methyl-1H-pyrazol-3-yl)amino)pyrimidin-2-yl)cyclohexane-1-carboxamide
Koodhka dhoola cadeynta:
CC1=NC([C@@H]2CC[C@] (OC)CC2=NC(NC5=NNC(C)=C5)=C1
Koodhka InChi:
InChi=1S/C28H33FN8O2/c1-17-13-24(33-25-14-18(2)35-36-25)34-26(31-17)21-9-11-28(39-4, 12-10-21)27 (38)32-19 (3)20-5-7-23 (8-6-20)37-16-22 (29)15-30-37/h5-8,13- 16,19,21H,9-12H2,1-4H3,(H,32,38)(H2,31,33,34,35,36)/t19-,21-,28+/m0/s1
Furaha InChi:
HUQPYQIGHTXBNW-BDHWGLMFSA-N
Ereyga muhiimka ah:
BLU-667; BLU 667; BLU667
Xalka:DMSO
Kaydinta:
Sharaxaad:
BLU-667 waa horjooge awood leh oo doorta is beddellada RET, fiyuusyada, iyo mutants adkaysiga la saadaaliyay. Fiyuusyada RET waa darawallada ugu muhiimsan ee kansarrada badan, oo ay ku jiraan sambabada iyo kansarka tayroodh, cilmi-baaristeenna waxay soo jeedinaysaa in RET ay sidoo kale door muhiim ah ka qaadato qaar ka mid ah kansarka mindhicirka iyo naasaha. Iyadoo isku mar la beegsanayo darawalka aasaasiga ah iyo mutants adkeysi la saadaaliyay oo unugyada kansarka ka dhigaya kuwo aan dareen ka lahayn daaweynta daawooyinka hadda la ansixiyay,
Ujeedka: RET