Ziftomenib ； KO539

Izina ryimiti:

(S) -4-Methyl-5 - ((4 - ((2- (methylamino)) -6- -1-yl) methyl) -1- (2- (4- (methylsulfonyl) piperazin-1-yl) propyl) -1H-indole-2-karubone

Kode ya SMILES:

N # CC (N1C [C @@ H] (N2CCN (S (= O) (C) = O) CC2) C) = CC3 = C1C = CC (CN4CCC (NC5 = C (C = C (CC (F))) (F) F) S6) C6 = NC (NC) = N5) CC4) = C3C

InChi Code:

InChI = 1S / C33H42F3N9O2S2 / c1-21 (43-11-13-44 (14-12-43) 49 (4,46) 47) 19-45-25 (18-37) 15-27-22 (2) 23 (5-6-29 (27) 45) 20-42-9-7-24 (8-10-42 ) 39-30-28-16-26 (17-33 (34,35) 36) 48-31 (28) 41-32 (38-3) 40-30 / h5-6,15-16,21,24H , 7-14,17,19-20H2,1-4H3, (H2,38,39,40,41) / t21- / m0 / s1

InChi Urufunguzo:

BGGALFIXXQOTPY-NRFANRHFSA-N

Ijambo ryibanze:

2134675-36-6 ； CAS ： 2134675-36-6 ； CAS: 2134675-36-6 ； Ziftomenib; KO539; KO 539; KO-539

Gukemura:Kwiyemeza

Ububiko:Kuma, umwijima no kuri 0 - 4 C mugihe gito (iminsi kugeza ibyumweru) cyangwa -20 C mugihe kirekire (amezi kugeza kumyaka).

Ibisobanuro:

Ziftomenib (KO-539) ni inhibitor ya menin MLL imikoranire nibikorwa byo munwa.

Intego: menin-MLL