Sildenafil Citrate

Izina ryimiti:

5- (2-ethoxy-5 - ( 7-imwe 2-hydroxypropane-1,2,3-tricarboxylate

Kode ya SMILES:

"CCCC1 = NN (C2 = C1NC (= NC2 = O) C3 = C (C = CC (= C3) S (= O) (= O) N4CCN (CC4) C) OCC) CC (C (= O) O ) C (CC (= O) O) (C (= O) O) O "

InChi Code:

InChI = 1S / C22H30N6O4S.C6H8O7 / c1-5-7-17-19-20 (27 (4) 25-17) 22 (29) 24-21 (23-19) 16-14-15 (8-9- 18 (16) 32-6-2) 33 (30,31) 28-12-10-26 (3) 11-13-28; 7-3 (8) 1-6 (13,5 (11) 12) 2-4 (9) 10 / h8-9,14H, 5-7,10-13H2,1-4H3, (H, 23,24,29); 13H, 1-2H2, (H, 7,8) ( H, 9,10) (H, 11,12)

InChi Urufunguzo:

DEIYFTQMQPDXOT-UHFFFAOYSA-N

Ijambo ryibanze:

Citrate ya Sildenafil ； UK 92480-10 ； UK-92,480-10 ； Revatio ； VIAGRA ； 171599-83-0 ； CAS: 171599-83-0 ； CAS ： 171599-83-0

Gukemura:Gukemura muri DMSO

Ububiko:0 - 4 ° C mugihe gito (iminsi kugeza ibyumweru), cyangwa -20 ° C mugihe kirekire (amezi)

Ibisobanuro:

Sildenafil, Citrate ni citrate ya Sildenafil. Sildenafil ni inhibitori ya PDE5 (ubwoko bwa 5 cGMP phosphodiesterase) itera hydrolysis ya 3 ', 5'-cyclic guanosine monophosphate (cGMP). Nka inhibitori ya PDE5, Sildenafil yavuzwe ko izamura neuro-, synapto- na angiogenezi muburyo bwimbeba ya stroke kandi bivugwa ko ari vasodilator yoroheje. Sildenafil yerekanwe kandi kugirango irinde indomethacine iterwa no gutera ibisebe bito byo mu mara binyuze mu buryo bwa NO / cGMP.

Intego: PDE5