Resmetirom

Izina ryimiti:

Resmetirom

Kode ya SMILES:

N # CC1 = NN (C2 = CC (Cl) = C (OC (C = C3C (C) C) = NNC3 = O) C (Cl) = C2) C (NC1 = O) = O

InChi Code:

InChI = 1S / C17H12Cl2N6O4 / c1-7 (2) 9-5-13 (22-23-15 (9) 26) 29-14-10 (18) 3-8 (4-11 (14) 19) 25- 17 (28) 21-16 (27) 12 (6-20) 24-25 / h3-5,7H, 1-2H3, (H, 23,26) (H, 21,27,28)

InChi Urufunguzo:

FDBYIYFVSAHJLY-UHFFFAOYSA-N

Ijambo ryibanze:

MGL-3196; MGL 3196; VIA 3196; VIA-3196; Resmetirom

Gukemura:Gukemura muri DMSO, ntabwo biri mumazi

Ububiko:0 - 4 C mugihe gito (iminsi kugeza ibyumweru), cyangwa -20 C mugihe kirekire (amezi)

Ibisobanuro:

Resmetirom, izwi kandi nka MGL-3196, ni reseptor ikomeye kandi itoranya cyane ya tiroyide ya hormone reseptor β agonist mu bigeragezo bivura indwara ya dyslipidemiya. Ingaruka nziza za hormone ya tiroyide (TH) kurwego rwa lipide ahanini ziterwa nigikorwa cyayo kuri reseptor ya hormone ya tiroyide β (THR-β) mu mwijima, mugihe ingaruka mbi, harimo ningaruka z'umutima, zahujwe na hormone ya tiroyide α (THR) -α).

Intego: THR-β