PCO371

Izina ryimiti:

1- (3,5-dimethyl-4- (2 - ((4-oxo-2- (4- (trifluoromethoxy) fenyl) -1,3,8-triazaspiro [4.5] dec-1-en-8-yl ) sulfonyl) ethyl) fenyl) -5,5-dimethylimidazolidine-2,4-dione

Kode ya SMILES:

O = C1NC (C (C) (C) N1C2 = CC (C) = C (CCS (= O) (N (CC3) CCC3 (N = C (C4 = CC = C (OC (F) (F) F) F) ) C = C4) N5) C5 = O) = O) C (C) = C2) = O.

InChi Code:

InChI = 1S / C29H32F3N5O6S / c1-17-15-20 (37-26 (40) 34-24 (38) 27 (37,3) 4) 16-18 (2) 22 (17) 9-14-44 ( 41,42) 36-12-10-28 (11 -13-36) 25 (39) 33-23 (35-28) 19-5-7-21 (8-6-19) 43-29 (30,31) 32 / h5-8,15-16H, 9 -14H2,1-4H3, (H, 33,35,39) (H, 34,38,40)

InChi Urufunguzo:

LDZJFVOUPUFOHX-UHFFFAOYSA-N

Ijambo ryibanze:

PCO371; PCO-371; PCO 371

Gukemura: 

Ububiko: 

Ibisobanuro:

PCO371 ni PTHR1 agonist ikomeye kandi ihitamo kuvura hypoparathyroidism. Ubuyobozi bwo mu kanwa bwa PCO371 kugeza imbeba osteopenic butera kwiyongera gukabije kwamagufwa hamwe no kwiyongera kwinshi kwamagufwa. Imbeba za hypocalcemic, PCO371 igarura urugero rwa calcium ya calcium itarinze kongera calcium yinkari, kandi hamwe ningaruka zikomeye kandi ziramba kuruta inshinge za PTH.

Intego: PTHR1