Luxdegalutamide; ARV-766

Izina ryimiti:

4- (4 - ((1- (4 - (((1r, 3r) -3- yl) methyl) piperazin-1-yl) -N - ((S) -2,6-dioxopiperidin-3-yl) -2-fluorobenzamide

Kode ya SMILES:

CC1 (C) [C @ H] (NC (C2 = CC = C (N3CCC (CN4CCN (C5 = CC (F) = C)) CC6) = O) C = C5) CC4) CC3) C = C2) = O) C (C) (C) [C @ H] 1OC1 = CC (OC) = C (C # N) C = C1

InChi Code:

InChI = 1S / C45H54FN7O6 / c1-44 (2) 42 (45 (3,4) 43 (44) 59-33-12-8-30 (26-47) 37 (25-33) 58-5) 50- 39 (55) 29-6-9-31 (10-7-29) 52-18-16-28 (17-19-52) 27-51-20-22-53 (23-21-51) 32- 11-13-34 (35 (46) 24-32) 40 (56) 48-36-14-15-38 (54) 49-41 (36) 57 / h6-13,24-25,28,36, 42-43H, 14-23,27H2,1-5H3, (H, 48,56) (H, 50,55) (H, 49,54,57) / t36-, 42-, 43- / m0 / s1

InChi Urufunguzo:

RDPPBRKNBBXPNZ-FMPIRMQTSA-N

Ijambo ryibanze:

2750830-09-0 ； CAS ： 2750830-09-0 ； CAS: 2750830-09-0 ； ARV766; ARV 766; ARV-766; GTPL12624; luxdegalutamide

Gukemura: 

Ububiko:Kuma, umwijima no kuri 0 - 4 C mugihe gito (iminsi kugeza ibyumweru) cyangwa -20 C mugihe kirekire (amezi kugeza kumyaka).

Ibisobanuro:

Luxdegalutamide (ARV-766) ni poroteyine hydrolysis ikora mu kanwa igamije chimeric (PROTAC) yibasira reseptor ya androgene (AR), ishobora gutesha agaciro ihinduka ry’imiterere ya AR.

Intego: AR