Etoricoxib

Izina ryimiti:

5-Chloro-6'-methyl-3- [4- (methylsulfonyl) fenyl] -2,3'-bipyridine

Kode ya SMILES:

O = S (C1 = CC = C (C2 = CC (Cl) = CN = C2C3 = CC = C (C) N = C3) C = C1) (C) = O

InChi Code:

InChI = 1S / C18H15ClN2O2S / c1-12-3-4-14 (10-20-12) 18-17 (9-15 (19) 11-21-18) 13-5-7-16 (8-6- 13) 24 (2,22) 23 / h3-11H, 1-2H3

InChi Urufunguzo:

MNJVRJDLRVPLFE-UHFFFAOYSA-N

Ijambo ryibanze:

Etoricoxib, Arcoxia, L-791456, MK 0663, MK-0663, 202409-33-4

Gukemura:Gukemura muri DMSO

Ububiko:0 - 4 ° C mugihe gito (iminsi kugeza ibyumweru), cyangwa -20 ° C mugihe kirekire (amezi)

Ibisobanuro:

Etoricoxib ni imiti ikora, idafite imiti igabanya ubukana (NSAID) ifite antipyretike, analgesic, hamwe na antineoplastique. Etoricoxib ihuza cyane kandi ikabuza enzyme cyclooxygenase-2 (COX-2), bikaviramo kubuza ihinduka rya acide arachidonic muri prostaglandine. Kubuza COX-2 birashobora gutera apoptose no kubuza ikwirakwizwa ryikibyimba na angiogenez.

Intego: COX-2