Divarasib, GDC 6036

Izina ryimiti:

1 - ((S) -4- (7 - ((R) -6-amino-4-methyl-3- (trifluoromethyl) pyridin-2-yl) -6-chloro-8-fluoro-2 - (((( S) -1-methylpyrrolidin-2-yl) imikorerexy) quinazolin-4-yl) -3-methylpiperazin-1-yl) prop-2-en-1-imwe

Kode ya SMILES:

NC1 = N [C @] ([C @] 2 = C (C = C3C (N = C (N = C3N4 [C @ H] (CN (CC4) C (C = C) = O) C) OC [ C @ H] 5N (CCC5) C) = C2F) Cl) = C (C (C) = C1) C (F) (F) F

InChi Code:

InChI = 1S / C29H32ClF4N7O2 / c1-5-21 (42) 40-9-10-41 (16 (3) 13-40) 27-18-12-19 (30) 22 (26-23 (29 (32, 33) 34) 15 (2) 11-20 (35) 36-26) 24 (31) 25 (18) 37-28 (38-27) 43-14-17-7-6-8-39 (17) 4 / h5,11-12,16-17H , 1,6-10,13-14H2,2-4H3, (H2,35,36)

InChi Urufunguzo:

ZRBPIAWWRPFDPY-UHFFFAOYSA-N

Ijambo ryibanze:

2417987-45-0; CAS: 2417987-45-0; CAS ： 2417987-45-0; Divarasib; GDC 6036

Gukemura:Gukemura

Ububiko:Kuma, umwijima no kuri 0 - 4 C mugihe gito (iminsi kugeza ibyumweru) cyangwa -20 C mugihe kirekire (amezi kugeza kumyaka).

Ibisobanuro:

Divarasib (GDC-6036) ni inhibitor ya KRAS G12C hamwe na bioavailable yo mu kanwa no guhitamo.

Intego: Inhibitor ya KRAS G12C