AZD0780;EX-A6975;laroprovstatum; laroprovstat

Navê Kîmyayî:

6'-(((1S,3S)-3-((5-(dîfluorometoksi)pîrîmîdîn-2-îl)amino)cyclopentyl)amino)-2H-[1,3'-bipyridin]-2-one

Koda SMILES:

O=C1N(C=CC=C1)C2=CN=C(N[C@@H]3C[C@H](CC3)NC4=NC=C(OC(F)F)C=N4)C= C2

Koda InChi:

InChI=1S/C20H20F2N6O2/c21-19(22)30-16-11-24-20(25-12-16)27-14-5-4-13(9-14)26-17-7-6- 15(10 -23-17)28-8-2-1-3-18(28)29/h1-3,6-8,10-14,19H,4-5,9H2,(H,23,26)(H ,24,25,27)/t13-,14-/m0/s1

Bişkojka InChi:

NCHUWRLOTSAFFN-KBPBESRZSA-N

Keyword:

2455427-91-3；CAS：2455427-91-3；CAS:2455427-91-3；AZD0780; AZD0780; AZD0780; EX-A6975; EX-A 6975; EXA6975; laroprovstatum; laroprovstat

Çareserî: 

Embarkirinî:Hişk, tarî û di 0 -4 C de ji bo demek kurt (roj heta hefte) an -20 C ji bo demek dirêj (mehan heta salan).

Terîf:

PCSK9-IN-12 pêkhateyek heteroaromatic e. PCSK9-IN-12 ji bo PCSK9 bi nirxek Kd ve girêdayî ye<200 nM. PCSK9-IN-12 dikare ji bo lêkolîna metabolîzma kolesterolê were bikar anîn.

Armanc: PCSK9