Ziftomenib;KO539

Aha:(S) -4-Methyl-5- ((4- (2- (methylamino)) -6- (2,2,2-trifluoroethyl) thieno (2,3-d) pyrimidin-4-yl) amino) piperidin -1-yl) methyl -1- (2- (4- (methylsulfonyl) piperazin-1-yl) propyl) -1H-indole-2-carbonitrile

Nọmba katalọgụ:CPD113642

Nọmba CAS:2134675-36-6

Ibu Molecular:717.87

Usoro kemịkalụ:C33 H42 F3 N9 O2 S2

Maka nyocha sayensị naanị, ọ bụghị maka ndị ọrịa.

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Nkọwa ngwaahịa

Mkpado ngwaahịa

Nha ngwugwu	Nnweta	Ọnụ ego (USD)
0.1G	Dị na ngwaahịa	650
0.5G	Dị na ngwaahịa	970
1G	Dị na ngwaahịa	1350

Aha kemịkalụ:

(S) -4-Methyl-5- ((4- (2- (methylamino)) -6- (2,2,2-trifluoroethyl) thieno (2,3-d) pyrimidin-4-yl) amino) piperidin -1-yl) methyl -1- (2- (4- (methylsulfonyl) piperazin-1-yl) propyl) -1H-indole-2-carbonitrile

Koodu Ọchịchọ:

N#CC(N1C[C@@H](N2CCN(S(=O)(C)=O)CC2)C=CC3=C1C=CC(CN4CCC(NC5=C(C=C(CC(F)) (F)F)S6)C6=NC(NC)=N5)CC4)=C3C

Koodu InChi:

InChi=1S/C33H42F3N9O2S2/c1-21(43-11-13-44(14-12-43)49(4,46)47) 19-45-25 (18-37)15-27-22 (2)23 (5-6-29 (27)45)20-42-9-7-24(8-10-42) )39-30-28-16-26(17-33(34,35)36)48-31(28)41-32(38-3)40-30/h5-6, 15-16,21,24H,7-14,17,19-20H2,1-4H3,(H2,38,39,40,41)/t21-/m0/s1

Igodo InChi:

BGGALFIXXQOTPY-NRFANRHFSA-N

Okwu:

2134675-36-6;CAS:2134675-36-6;CAS:2134675-36-6;Ziftomenib; KO539; KO 539; KO-539

Solubility:Iji kpebisie ike

Nchekwa:Akọrọ, ọchịchịrị na na 0 - 4 C maka obere oge (ụbọchị ruo izu) ma ọ bụ -20 C maka ogologo oge (ọnwa ruo afọ).

Nkọwa:

Ziftomenib (KO-539) bụ onye na-egbochi mmekọrịta nke menin MLL na ọrụ ọnụ.

Ebumnuche: menin-MLL

Nke gara aga: 4,6-dichloro-5-fluoro-2-Methanesulfonyl-pyriMidine

Osote: N-Methyl-5- (piperazin-1-yl) picolinamide hydrochloride