agonist-3

Aha kemịkalụ:

(E) -1- (4- (5-carbamoyl-2-- (1-ethyl-3-methyl-1H-pyrazole-5-carboxamido) -1H-benzo [d] imidazole-1-yl) ma-2- en-1- yl) -2- (1-ethyl-3-methyl-1H-pyrazole-5-carboxamido) -7- (3-hydroxypropoxy) -1H-benzo [d] imidazole-5-carboxamide

Koodu Ọchịchọ:

O=C(N)C1=CC=C(N(C(NC(C2=CC(C)=NN2CC)=O)=N3)C/C=C/CN4C5=C(N=C4NC(C6=CC) (C)=NN6CC)=O)C=C(C(N)=O)C=C5OCCCO)C3=C1

Koodu InChi:

InChi=1S/C37H42N12O6/c1-5-48-28(16-21(3)44-48)34(53)42-36-40-25-18-23(3) 2 (38)51 15-9-14-50)41-37(47)43-35(54)29-17-22(4)45-49(29)6-2/h7-8,10-11,16-20, 50 H,5-6,9,12-15H2,1-4H3,(H2,38,51)(H2,39,52)(H,40,42,53)(H,41,43,54)/b8 -7+

Igodo InChi:

VHCDRDBBENBVEK-BQYQJAHWSA-N

Okwu:

Solubility: 

Nchekwa: 

Nkọwa:

STING agonist-3, nke ewepụtara na patent WO2017175147A1 (ihe atụ 10), bụ nhọrọ na-abụghị nucleotide obere-molecule agonist nwere pEC50 na pIC50 nke 7.5 na 9.5, n'otu n'otu. STING agonist-3 nwere mmetụta mgbochi tumor na-adịgide adịgide yana ikike dị ukwuu iji meziwanye ọgwụgwọ ọrịa kansa

Ebumnuche: STING