SJ-01

Aha kemịkalụ:

(E) -1- (3- (3,4,5-trimethoxyphenyl)acryloyl) -5,6-dihydropyridin-2 (1H) -otu.

Koodu Ọchịchọ:

O=C1C=CCCN1C(/C=C/C2=CC(OC)=C(OC)C(OC)=C2)=O

Koodu InChi:

InChi=1S/C17H19NO5/c1-21-13-10-12(11-14(22-2)17(13)23-3)7-8-16(20)18-9-5-4-6- 15(18)19/h4,6-8,10-11H,5,9H2,1-3H3/b8-7+

Igodo InChi:

VABYUUZNAVQNPG-BQYQJAHWSA-N

Okwu:

20069-09-4;CAS:20069-09-4;CAS:20069-09-4;Piperlongumine; Piplatine.

Solubility:Soluble na DMSO

Nchekwa:Akọrọ, ọchịchịrị na na 0 - 4 C maka obere oge (ụbọchị ruo izu) ma ọ bụ -20 C maka ogologo oge (ọnwa ruo afọ).

Nkọwa:

Piperlongumine, nke a makwaara dị ka Piplartine, bụ alkaloid / amide sitere na ose, dị ka ose ogologo (Piper longum L. - Piperaceae). ose ogologo bụ otu n'ime ọgwụ Ayurvedic a na-ejikarị eme ihe, nke a na-eji agwọ ọtụtụ ọrịa, gụnyere etuto ahụ. Ihe omume ọgwụ a kọrọ na piplartine gụnyere cytotoxic, genotoxic, antitumor, antiangiogenic, antimetastatic, antiplatelet aggregation, antinociceptive, anxiolytic, antidepressant, anti-atherosclerotic, antidiabetic, antibacterial, antifungal, leishmanicidal, trypanocidal, na schid. N'ime ọtụtụ mmetụta ọgwụ ọgwụ nke piplartine, ihe onwunwe anticancer ya bụ ihe na-ekwe nkwa.

Ebumnuche: Piperlongumine bụ alkaloid nke na-egbochi mgbanwe nke myofibroblasts site na igbochi ụzọ akara erk1/2.