NST-628
Nkọwa ngwaahịa
Mkpado ngwaahịa
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Aha kemịkalụ:
3-[[3-fluoro-2- (methylsulfamoylamino) pyridin-4-yl] methyl]-7- (3-fluoropyridin-2-yl) oxy-4-methylchromen-2-otu
Koodu Ọchịchọ:
FC1=C(OC2=CC=C(C(C)=C(CC3=C(F)C(NS(NC)(=O)=O)=NC=C3)C(O4)=O)C4= C2)N=CC=C1
Koodu InChi:
InChi=1S/C22H18F2N4O5S/c1-12-15-6-5-14(32-21-17(23)4-3-8-27-21)11-18(15)33-22(29)16( 12)10-13-7-9-26-20(19(13)24)28-34(30,31)25-2/h3-9,11,25H,10H2,1-2H3,(H,26 ,28)
Igodo InChi:
YQSZJOABXRROQR-UHFFFAOYSA-N
Okwu:
3002056-30-3;CAS:3002056-30-3;CAS:3002056-30-3;NST-628;NST628;NST 628
Solubility:
Nchekwa:Akọrọ, ọchịchịrị na na 0 -4 C maka obere oge (ụbọchị ruo izu) ma ọ bụ -20 C maka ogologo oge (ọnwa ruo afọ).
Nkọwa:
NST-628 bụ gel molecular ụzọ MAPK nwere ikike mgbochi ụbụrụ ụbụrụ, nke nwere ike igbochi RAF phosphorylation na ịgbalite MEK.
Ebumnuche: RAF phosphorylation na MEK