GDC6036;GDC6036 atropisomers

GDC6036;GDC6036 atropisomers
  • Aha:2-Propen-1-otu, 1-[(3S) -4-[7-[6-amino-4-methyl-3- (trifluoromethyl) -2-pyridinyl]-6-chloro-8-fluoro-2- [[(2S) -1-methyl-2-pyrrolidinyl] methoxy] -4-quinazolinyl] -3-methyl-1-piperazinyl] -
  • Nọmba katalọgụ:CPD111670
  • Nọmba CAS:2417917-17-8
  • Arọ Molecular:622.06
  • Usoro kemịkalụ:C29 H32 Cl F4 N7 O2
  • Maka nyocha sayensị naanị, ọ bụghị maka ndị ọrịa.

    Nkọwa ngwaahịa

    Mkpado ngwaahịa

    Nha ngwugwu Nnweta Ọnụ ego (USD)
    0.1G Dị na ngwaahịa 870

    Aha kemịkalụ:

    2-Propen-1-otu, 1-[(3S) -4-[7-[6-amino-4-methyl-3- (trifluoromethyl) -2-pyridinyl]-6-chloro-8-fluoro-2- [[(2S) -1-methyl-2-pyrrolidinyl] methoxy] -4-quinazolinyl] -3-methyl-1-piperazinyl] -

    Koodu Ọchịchọ:

    C=CC(N1C[C@H](C)N(C2=C3C=C(Cl)C(C4=NC(N)=CC(C)=C4C(F)(F)F)=C(F)=C(F) )C3=NC(OC[C@H]5N(C)CCC5=N2)CC1)=O

    Koodu InChi:

    InChi=1S/C29H32ClF4N7O2/c1-5-21(42)40-9-10-41(16(3)13-40)27-18-12-19(30)22(26-23(29(32, 33)34)15(2)11-20(35)36-26)24(31)25(18)37-28(38-27)43-14-17-7-6-8-39(17) 4/h5,11-12,16-17H,1,6-10,13-14H2,2-4H3,(H2,35,36)/t16-,17-/m0/s1

    Igodo InChi:

    ZRBPIAWWRPFDPY-IRXDYDNUSA-N

    Okwu:

    2417917-17-8;CAS:2417917-17-8;CAS:2417917-17-8:GDC6036 atropisomers; GDC-6036; GDC 6036; GDC6036

    Solubility: 

    Nchekwa:Akọrọ, ọchịchịrị na na 0 - 4 C maka obere oge (ụbọchị ruo izu) ma ọ bụ -20 C maka ogologo oge (ọnwa ruo afọ).

    Nkọwa:

    GDC6036 mgbochi rotation isomer nwere ụdị abụọ nke GDC6036 mgbochi rotation isomer. GDC-6036, A makwaara dị ka RG6330, ọ bụ ihe na-eme ka ọnụ ọnụ dị ndụ, na-arụ ọrụ nke ọma, yana onye na-emechi KRAS G12C.

    Ebumnuche: KRAS G12C




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