Etoricoxib

Aha kemịkalụ:

5-Chloro-6'-methyl-3-[4- (methylsulfonyl) phenyl] -2,3'-bipyridine.

Koodu Ọchịchọ:

O=S(C1=CC=C(C2=CC(Cl)=CN=C2C3=CC=C(C)N=C3)C=C1)(C)=O

Koodu InChi:

InChi=1S/C18H15ClN2O2S/c1-12-3-4-14(10-20-12)18-17(9-15(19)11-21-18)13-5-7-16(8-6- 13)24 (2,22)23/h3-11H,1-2H3

Igodo InChi:

MNJVRJDLRVPLFE-UHFFFAOYSA-N

Okwu:

Etoricoxib, Arcoxia, L-791456, MK 0663, MK-0663, 202409-33-4

Solubility:Soluble na DMSO

Nchekwa:0 - 4 Celsius C maka obere oge (ụbọchị ruo izu), ma ọ bụ -20 Celsius maka ogologo oge (ọnwa)

Nkọwa:

Etoricoxib bụ ọgwụ sịntetik, ọgwụ na-adịghị steroidal anti-inflammatory (NSAID) nwere antipyretic, analgesic, na ihe nwere ike antineoplastic. Etoricoxib na-ejikọta kpọmkwem ma na-egbochi enzyme cyclooxygenase-2 (COX-2), na-ebute nkwụsị nke ntụgharị nke arachidonic acid n'ime prostaglandins. Mgbochi nke COX-2 nwere ike ịkpata apoptosis ma gbochie mmụba cell tumo na angiogenesis.

Ebumnuche: COX-2