Chenodeoxycholic acid

Aha kemịkalụ:

(R) -4-((3R,5S,7R,8R,9S,10S,13R,14S,17R) -3,7-dihydroxy-10,13-dimethylhexadecahydro-1H-cyclopenta[a] phenanthren-17-yl Penanoic acid

Koodu Ọchịchọ:

C[C@H]([C@H] 1CC[C @] 2([H])[C@] 3([H])[C@H](O)C[C@] 4( [H])C[C@H](O)CC[C@]4(C)[C@@]3([H])CC[C@]12C)CCC(O)=O

Koodu InChi:

InChi=1S/C24H40O4/c1-14(4-7-21(27)28)17-5-6-18-22-19(9-11-24(17,18)3)23(2)10- 8-16 (25) 12-15 (23)13-20 (22)26/h14-20,22,25-26H,4-13H2,1-3H3,(H,27,28)/t14-,15 +,16-,17-,18+,19+,20-,22+,23+,24-/m1/s1

Igodo InChi:

RUDATBOHQWOJDD-BSWAIDMHSA-N

Okwu:

474-25-9, CAS: 474-25-9, CAS: 474-25-9, Chenodeoxycholic Acid, Anthropodeoxycholic acid, Anthropodesoxycholic acid, CCRIS 2195, Chendol, chenic acid; Chenix, Chenodeoxycholic acid, Chenodesoxycholic acid, Chenodiol, Gallodesoxycholic acid, NSC 657949, Xenbilox

Solubility:Soluble na DMSO, ọ bụghị na mmiri

Nchekwa:Akọrọ, ọchịchịrị na na 0 - 4 C maka obere oge (ụbọchị ruo izu) ma ọ bụ -20 C maka ogologo oge (ọnwa ruo afọ)

Nkọwa:

Chenodiol, nke a makwaara dị ka Chenodeoxycholic Acid na chenocholic acid, bụ bile acid. Ọ na-eme dị ka ihe na-acha ọcha kristal nke a na-apụghị ịsacha n'ime mmiri ma na-agbaze na mmanya na acetic acid, na-agbaze na 165-167 Celsius. A na-akpọ nnu nke acid carboxylic a chenodeoxycholates. Ejila Chenodeoxycholic acid dị ka ọgwụgwọ ahụike iji gbazee nkume gallstones. Enwere ike iji Chenodeoxycholic acid na ọgwụgwọ nke xanthomatosis cerebrotendineous. Ụlọ ọrụ biotechnology nke Australia Giaconda anwalela ọgwụgwọ maka ọrịa ịba ọcha n'anya C nke jikọtara chenodeoxycholic acid na bezafibrate.

Ebumnuche: FXR ihe nnata nuklia arụ ọrụ