BMS-986408 IB

Lub npe tshuaj:

4-((2S,5R)-2,5-diethyl-4-((S)-1-(4-(trifluoromethyl)phenyl)propyl)piperazin-1-yl)-1-methyl-2-oxo-1 ,2-dihydropyrido [3,2-d] pyrimidine-6-carbonitrile

SMILES Code:

CC[C@H]1CN([C@@H](CN1C2=NC(N(C3=CC=C(N=C32)C#N)C)=O)CC)[C@H](C4= CC=C(C=C4)C(F)(F)F)CC

InChi Code:

InChI=1S/C27H31F3N6O/c1-5-20-16-36(25-24-23(34(4)26(37)33-25)13-12-19(14-31)32-24)21( 6-2) 15- 35(20)22(7-3)17-8-10-18(11-9-17)27(28,29)30/h8-13,20-22H,5-7,15-16H2,1- 4H3/t20-,21+,22+/m1/s1

InChi Key:

MVPFPBIHUUHXGU-FSSWDIPSSA-N

Lo lus tseem ceeb:

2618418-12-3; CAS: 2618418-12-3; CAS: 2618418-12-3; BMS-986408; BMS986408; TIAB SA 986408

Solubility: 

Cia:Qhuav, tsaus thiab ntawm 0 -4 C rau lub sijhawm luv (hnub mus rau lub lis piam) lossis -20 C rau lub sijhawm ntev (hli mus rau xyoo).

Nqe lus piav qhia:

BMS-986408 yog ib qho kev hais lus zoo dual DGK α / Zeta inhibitor.

Hom phiaj: DGK α/ζ